Ph.D.
Research Areas:
Cardiovascular Pharmacology
Education & Positions:
Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University, research associate, 2010-
Peking Union Medical College, Ph.D in Microbial and Biochemical Pharmacy, 2007-2010
Sichuan University, Master degree in Pathogenic Microbiology, 2004-2007
Sichuan University, Bachelor degree in Basic Medicine, 1999-2004
Research Interests:
My major research focuses on the protein/peptide design for the treatment of stroke/thrombosis, and identify the mechanism of neuroprotective agents.
Grants and fundings:
1. Title: Exogenous hydrogen sulfide protects against cerebral ischemia/reperfusion injury via its anti-autophagy effects
Fund source: National Natural Science Foundation of China
Fund amount: 230, 000 CNY
Identity: Principal / Main undertaker (2014-2016)
2. Title: Honokinol protects against cerebral ischemia/reperfusion injury via its anti-autophagy effects
Fund source: Beijing Natural Science Foundation
Fund amount: 80, 000 CNY
Identity: Principal / Main undertaker (2014-2015)
Selected Publications
1. Yuanjun Zhu, Yuan Lin, Aihua Liu, Mengyang Shui, Ruyi Li, Xiaoyan Liu, Wenhui Hu, Yinye Wang. Structure-guided creation of AcAP5-derived and platelet targeted factor Xa inhibitors. Biochemical Pharmacology. 2015, 95(4):253-62.
2. Yuanjun Zhu#, Yuanqing Gao#, Danping Zheng#, Mengyang Shui, Kuai Yu, Xiaoyan liu, Yuan Lin, Li Su, Wenxing Yang, Yinye Wang*. Design and evaluation of EphrinA1 mutants with cerebral protective effect. Scientific Reports, 2017; 7: 1881.
3. Yuanjun Zhu#, Ruyi Li#, Yuan Lin, Mengyang Shui, Xiaoyan Liu, Huan Chen, Yinye Wang*. Engineering Factor Xa Inhibitor with Multiple Platelet-Binding Sites Facilitates its Platelet Targeting. Scientific Reports. 2016, 6: 29895.
4. Yuanjun Zhu#, Qixin Bu#, Xiaoyan Liu, Wenhui Hu, Yinye Wang*. Neuroprotective Effect of TAT-14-3-3 epsilon Fusion Protein against Cerebral Ischemia/Reperfusion Injury in Rats. PLoS One. 2014, 9(3): e93334.
5. Yuanjun Zhu#, Aihua Liu#, Xiaoyan Liu, Yinye Wang*. Engineering Novel Anticoagulant Proteins by Motif Grafting. Protein and Peptide Letters. 2014, 21(2):159-63.
