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2015年代表论文

1.     Hao YC, Tang JS, Wang KW. Development of Automated Patch Clamp Assay for Evaluation of alpha 7 Nicotinic Acetylcholine Receptor Agonists in Automated QPatch-16. Assay and Drug Development Technologies 2015;13:174-184.

2.     Jia LH, Liu W, Guan LZ, Lu M, Wang KW. Inhibition of Calcium-Activated Chloride Channel ANO1/TMEM16A Suppresses Tumor Growth and Invasion in Human Lung Cancer. Plos One 2015;10.

3.     Li HF, Liu XY, Zhu YJ, Liu Y, Wang YY. Magnolol derivative 002C-3 protects brain against ischemia-reperfusion injury via inhibiting apoptosis and autophagy. Neuroscience Letters 2015;588:178-183.

4.     Liu YG, Li XX, Xiong DC, Yu BH, Pu XP, Ye XS. Synthetic phenylethanoid glycoside derivatives as potent neuroprotective agents. European Journal of Medicinal Chemistry 2015;95:313-323.

5.     Ren R, Shi C, Cao J, Sun Y, Zhao X, Guo Y, Wang C, et al. Neuroprotective Effects of A Standardized Flavonoid Extract of Safflower Against Neurotoxin-Induced Cellular and Animal Models of Parkinson's Disease. Sci Rep 2016;6:22135.

6.     Ren RT, Sun Y, Zhao X, Pu XP. Recent advances in biomarkers for Parkinson's disease focusing on biochemicals, omics and neuroimaging. Clinical Chemistry and Laboratory Medicine 2015;53:1495-1506.

7.     Tang JS, Xie BX, Bian XL, Xue Y, Wei NN, Zhou JH, Hao YC, et al. Identification and in vitro pharmacological characterization of a novel and selective alpha7 nicotinic acetylcholine receptor agonist, Br-IQ17B. Acta Pharmacol Sin 2015;36:800-812.

8.     Wan D, Wang D, Sun Q, Song Y, Jiang YM, Li RT, Ye J. Antinociception of spirocyclopiperazinium salt compound LXM-10-M targeting alpha 7 nicotinic receptor and M4 muscarinic receptor and inhibiting CaMKII alpha/CREB/CGRP signaling pathway in mice. European Journal of Pharmacology 2016;770:92-98.

9.     Wang J, Tan HL, Sun Q, Ge ZM, Wang X, Wang YY, Li RT. Design, synthesis and biological evaluation of pyridazino[3,4,5-de]quinazolin-3(2H)-one as a new class of PARP-1 inhibitors. Bioorganic & Medicinal Chemistry Letters 2015;25:2340-2344.

10.   Wang Y, Mi J, Lu K, Lu Y, Wang K. Comparison of Gating Properties and Use-Dependent Block of Nav1.5 and Nav1.7 Channels by Anti-Arrhythmics Mexiletine and Lidocaine. PLoS One 2015;10:e0128653.

11.   Yang S, Yang F, Wei N, Hong J, Li B, Luo L, Rong M, et al. A pain-inducing centipede toxin targets the heat activation machinery of nociceptor TRPV1. Nat Commun 2015;6:8297.

12.   Zhou JH, Tang YQ, Zheng Q, Li M, Yuan TY, Chen LY, Huang Z, et al. Different KChIPs Compete for Heteromultimeric Assembly with Pore-Forming Kv4 Subunits. Biophysical Journal 2015;108:2658-2669.

13.   Zhou JJ, Zhai SY, Zhang HN, Wang YH, Pu XP. Neuroprotective effects of 3-O-demethylswertipunicoside against MPTP-induced Parkinson's disease in vivo and its antioxidant properties in vitro. Brain Res 2015;1624:78-85.

14.   Zhu YJ, Lin Y, Liu AH, Shui MY, Li RY, Liu XY, Hu WH, et al. Structure-guided creation of AcAP5-derived and platelet targeted factor Xa inhibitors. Biochemical Pharmacology 2015;95:253-262.