朱元军，男，博士，北京大学药学院讲师。在Biochemical Pharmacology、Scientific reports等杂志上发表多篇论文，以及发明专利3项。主持国家自然科学基金（青年基金）1项和北京市自然基金（青年基金）1项，参与多个项目研究。

研究方向：神经保护剂、靶向抗凝

电话：(010)-8280 1703(办公室)

E-mail:zhuyuanjun@bjmu.edu.cn

教育经历：

2007-2010年，北京协和医学院， 博士。

1999-2007年，四川大学华西医学中心，本科，硕士。

 发表文章：

 

1. Yuanjun Zhu, Yuan Lin, Aihua Liu, Mengyang Shui, Ruyi Li, Xiaoyan Liu, Wenhui Hu, Yinye Wang. Structure-guided creation of AcAP5-derived and platelet targeted factor Xa inhibitors. Biochemical Pharmacology. 2015, 95(4):253-62.
2. Yuanjun Zhu#, Yuanqing Gao#, Danping Zheng#, Mengyang Shui, Kuai Yu, Xiaoyan liu, Yuan Lin, Li Su, Wenxing Yang, Yinye Wang*. Design and evaluation of EphrinA1 mutants with cerebral protective effect. Scientific Reports, 2017; 7: 1881.
3. Yuanjun Zhu#, Ruyi Li#, Yuan Lin, Mengyang Shui, Xiaoyan Liu, Huan Chen, Yinye Wang*. Engineering Factor Xa Inhibitor with Multiple Platelet-Binding Sites Facilitates its Platelet Targeting. Scientific Reports. 2016, 6: 29895.
4. Yuanjun Zhu#, Mengyang Shui#, Xiaoyan Liu, Wenhui Hu*, Yinye Wang*.Increased autophagic degradation contributes to the neuroprotection of hydrogen sulfide against cerebral ischemia/reperfusion injury. Metabolic Brain Disease, 2017, doi: 10.1007/s11011-017-0014-4.
5. Yuanjun Zhu#, Tongliang Zhou#, Lingfei Yang, Lan Yuan, Lei Liang*, Ping Xu*.Revelation of the dynamic progression of hypoxia-reoxygenation injury by visualization of the lysosomal hydrogen peroxide. Biochemical & Biophysical Research Communication, 2017, 486 (4):904-908.
6. Tongliang Zhou, Lingfei Yang, Lei Liang*, Hui Liu, Yuanjun Zhu*, Mengyang Shui, Lan Yuan*, Fengrong Xu, Yan Niu, Chao Wang, and Ping Xu*. Rational Design of a Near-infrared Fluorescent Probe Based on Pyridazinone Scaffold. European Journal of Organic Chemistry. 2017, 3274–3281.
7. Lingfei Yang#, Yuanjun Zhu#, Mengyang Shui, Tongliang Zhou, Yuanbo Cai, Wei Wang, Fengrong Xu, Yan Niu, Chao Wang, Ping Xu*, Lan Yuan*, Lei Liang*. Rational Design of Fluorescent Phthalazinone Derivatives for One- and Two-Photon Imaging. Chemistry - A European Journal. 2016, 22(35):12363-70.
8. Yuanjun Zhu#, Qixin Bu#, Xiaoyan Liu, Wenhui Hu, Yinye Wang*. Neuroprotective Effect of TAT-14-3-3 epsilon Fusion Protein against Cerebral Ischemia/Reperfusion Injury in Rats. PLoS One. 2014, 9(3): e93334.
9. Yuanjun Zhu#, Yuan Lin#, Xiaoyan Liu, Wenhui Hu*, Yinye Wang*. Identification of AcAP5 as a novel factor Xa inhibitor with both direct and allosteric inhibition. Biochemical and Biophysical Research Communications, 2017, 483(1):495-501.
10. Yuanjun Zhu#, Aihua Liu#, Xiaoyan Liu, Yinye Wang*. Engineering Novel Anticoagulant Proteins by Motif Grafting. Protein and Peptide Letters. 2014, 21(2):159-63.
11. Mengyang Shui, Xiaoyan Liu, Yuanjun Zhu*, Yinye Wang*. Exogenous hydrogen sulfide attenuates cerebral ischemia-reperfusion injury by inhibiting  autophagy in mice. Canadian Journal of Physiology and Pharmacology, 2016, 94(11): 1187-1192.

     

专利：

1. 王银叶、高远晴、朱元军、刘晓岩、张烨. 重组生促红素肝细胞受体A2拮抗剂及其编码基因和应用201510191121.3
2. 王银叶，丁双，刘晓岩，朱元军。犬钩虫抗凝肽及其突变体在制备溶血栓药物中的应用途。2011.04，中国，201110106956.6。
3. 洪斌，朱元军，王丽非，杜郁，余腾斐，王松梅。一种新型链霉菌分泌表达质粒及应用。2010.06，中国，201010196933.4。